629 Improving Gentamicin Prescribing for Intra-Abdominal Sepsis on a General Surgical Firm

Abstract Aim Gentamicin is recommended by local guidelines for the empirical treatment of intra-abdominal sepsis. However, severe side effects that can occur through prolonged raised levels requires its use a specific dosing protocol. Challenges this means it often “falls off” drug chart, leading to suboptimal drug-levels. The aim quality improvement project was improve process gentamicin prescription. Method A two-week retrospective analysis all patients admitted performed obtain baseline data. Information collected on use, if were taken at 6–14 hours post-dose, and subsequently correctly re-prescribed. PDSA 1 involved placing posters in surgical office, reminding clerking doctor 2 departmental teaching session reiterate above intervention. Results At baseline, only 7% (1/15) prescribed had correct post-dose level received second dose. After 1, rose 67% (2/3). 2, similar 60% (3/5). Furthermore, 47% (15/32) deemed have sepsis gentamicin. proportion fell 11% (3/28) after 38% (5/13). Conclusions Education sessions effective increasing safely dose gentamicin, as result trough levels. reduction percentage receiving possibly suggests further education role required.